Cellular and Multicellular Technologies

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This program supports the development and demonstration of broadly applicable cellular and multicellular technologies to enable new paradigms of human health.

Emphasis:

The emphasis is on the development of cellular and multicellular technologies and associated computational models for biomedical intervention. 

Projects might focus on:

  • elucidating important engineering design rules or key foundational principles underlying future engineering, including the use of computational methods
  • prototyping or redesigning platform technologies
  • characterizing (in vitro, ex vivo, or in vivo) broadly applicable technologies and prototypes

NIBIB interests include but are not limited to: 

  • synthetic genetic circuits for cellular control and decision-making
  • engineered bacteria for microbiome regulation
  • engineered T-cells for immune regulation and cancer therapy
  • organoids and scaffold-free tissue assemblies for replacing organ function